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2021 update of the 2012 ICSH Recommendations for identification, diagnostic value, and quantitation of schistocytes: Impact and revision

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Hi friends, I am writing this post after a long time. Sorry about that. Hope you are all doing well.    The International Council for Standardization in Haematology (ICSH) published recommendations for the identification, quantitation, and diagnostic value of schistocytes in 2012.    What was the main focus of 2012 ICSH recommendations? Ø   Microscope evaluation method, Ø   Specific morphologic criteria for schistocyte Ø   Identification and percentage calculation, Ø   Definition of a threshold value in healthy subjects  Whats new in 2021 update ?  It is review of the effectiveness and clinical usefulness of the ICSH 2012 recommendations based on the published literature. Additional recommendations: ·          The study of preanalytical factors, ·          The context for reporting schistocyte percentage of clinical significance in the diagnosis of thrombotic microangiopathy (TMA) and transplant-associated TMA (TA-TMA), ·          Initial validation criteria for